Environmental, economic and social impacts


of fossil-based surfactants and siderophores production with cost-effective and ‘eco-friendly’ microbial production of marine-based compounds • Expected CO2 emissions reduction by 94% compared with existing practices • Fully exploitation of already sampled species to avoid environmental damages from sampling campaigns • Increasing carbon efficiency by ◦ maximizing product titres, yields and productivities using modified micro-organisms ◦ optimizing separation technologies for effective products recovery ◦ using side and waste streams as inputs for fermentation • Technological outcomes are expected to contribute to creation of new jobs by 1-2% in the entire industrial biotechnology value chain

Environmental, economic and social impacts

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  2. WP2 mpla

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  3. WP3

  4. WP4

  5. WP5

  6. WP6

  7. WP7

  8. WP8

  9. WP9

  10. WP10


Leader IDE R&D

The objective of this workpackage is to ensure compliance with the ethics requirements' set out in this work package

Leader MATIS

This WP focuses on developing and applying a range of high-throughput approaches for siderophore and biosurfactant biodiscovery. The objectives of this work package are to assemble provided diverse microbial collections; to select and optimise culture-based and culture-independent methods for screening procedure; to identify and explore taxonomical groups with active production of for biosurfactants and siderophores, and to identify the genetic elements in charge of the synthesis of targeted biosurfactants and siderophores.

Leader IDE R&D

This work package combines activities aimed to obtain genetic combination designs to produce new tailor-made biocompounds. Specifically, WP3 aims to: • the development of machine learning algorithms to survey databases and collect pathways, genetic information, molecular structures and properties of biosurfactants and siderophores. • the definition and construction of biosurfactant and siderophores chemical space. • the identification of major molecular structures with interesting properties. • the implementation of inverse QSAR/QSPR modelling approach.

Leader USE

The aim of this WP is to engineer bacterial strains with the capacity of overproducing new chemical designs. The specific goals include (i) adaptation and optimization of standardized vectors in extremophilic model organisms, (ii) the development of “ready to use” microbial strains and model-driven strain designs (iii) experimental validation of metabolism and gene expression model.

Leader UoA

In this WP protocols for production of small-scale quantities, from strains derived in WP1 and WP4 will be accomplished together with isolation and characterization of biosurfactants and siderophores.  Evaluation of the state of the art on extraction and purification procedures  Standardized protocols for chemical characterization  Determination of novel biosurfactant and siderophore chemical structures.

Leader BBEPP

The high-performing strains developed in WP5 will be used during the optimization of the operating strategy at pilot scale. The main objectives are: • Integration of unit operations in mathematical process model. • Core processes demonstration at pilot scale.

Leader SE

The overall goal of this WP is to characterise, analyse and investigate the efficacy of the identified bio-surfactants in the different end-user fields (oncology, gene delivery, cosmetic, house-hold and personal care, food industry/nutrition, agriculture) of the present consortium. WP7 includes the following methods and tests: • Bio-surfactants drug encapsulation, efficacy and toxicity profiles • Novel encapsulation approaches for different end-user applications • Immunomodulatory and anti-tumorigenic capacity of selected compounds • Efficacy of bio-compounds as chelating agents

Leader Blue Synergy

 Quantification and evaluation of environmental effects by the proposed technologies and products  Estimation of capital and operating expenses, cost-effectiveness and competitiveness of proposed solutions  Social impacts and social return of investment assessment  Consumer perception study, awareness campaigns and social acceptance analysis.


This work package aims to boost SECRETed’s impact and facilitate the introduction of the results to the market.  Dissemination and communication of project’s results and messages to target audiences: stakeholders and general public.  Detailed exploitation roadmap (Plan for Exploitation and Dissemination of Results) to bring project results to the market.  Mapping and management of the intellectual property rights.

Leader IDE R&D

The overall objective of this WP is to perform the project coordination and management according to the management structure and decision-making mechanisms of established for the SECRETed project.