Objectives of SECRETed Project
The objectives of the project are summarized as follows:
- To unlock the potential of marine and extremophilic bacteria for the development of tailor made amphiphilic molecules
- To screen and detect Biosynthetic gene clusters for the synthesis of biosurfactants and siderophores based on 4 different aquatic microbial collections
- To develop a genomic and chemical database including siderophore and biosurfactant production pathways and gene clusters, as well as their chemical structures and physiochemical properties.
- To formulate a ‘mix and match’ modelling pipeline, where ‘mixing’ of modular genetic elements is ‘matched’ with tailor-made compounds
- To characterize newly discovered and engineered compounds and optimize their production and purification methods
- To develop and validate a mathematical model for production process
- To demonstrate proposed solutions and developed microbial strains in pilot plant scale (TRL-6)
- To assess environmental, economic and social perspectives of the proposed solutions
