Accuplex has licenced a novel diagnostic application for detection of fungal siderophores, the first immunodiagnostic application for siderophore detection. The technology was developed by Professor Sean Doyle, Maynooth University, Ireland using both ELISA and lateral flow-based platforms. The addition of […]
Invasive pulmonary aspergillosis (IPA) is a severe life-threatening condition. Diagnosis of fungal disease in general, and especially that caused by Aspergillus fumigatus is problematic. A. fumigatus secretes siderophores to acquire iron during infection, which are also essential for virulence. We […]
On the 8th of February 2022, the 1st General Assembly meeting of SECRETed project was held remotely due to COVID-19 Pandemic. The General Assembly consists of one representative from each beneficiary participating in the SECRETed project and is chaired by […]
Emerging and re-emerging viruses represent a serious threat to human health at a global level. In particular, enveloped viruses are one of the main causes of viral outbreaks, as recently demonstrated by SARS-CoV-2. An effective strategy to counteract these viruses […]
Bacterial secondary metabolites have been studied for decades for their usefulness as drugs, such as antibiotics. However, the identification of new structures has been decelerating, in part due to rediscovery of known compounds. Meanwhile, multi-resistant pathogens continue to emerge, urging […]
Discovery of novel antibiotics is crucial for combating rapidly spreading antimicrobial resistance and new infectious diseases. Most of the clinically used antibiotics are natural products—secondary metabolites produced by soil microbes that can be cultured in the lab. Rediscovery of these […]
Environmental microorganisms continue to serve as a major source of bioactive natural products (NPs) and as an inspiration for many other scaffolds in the toolbox of modern medicine. Nearly all microbial NP-inspired therapies can be traced to field expeditions to […]
As a result of the continuous evolution of drug resistant bacteria, new antibiotics are urgently needed. Encoded by biosynthetic gene clusters (BGCs), antibiotic compounds are mostly produced by bacteria. With the exponential increase in the number of publicly available, sequenced […]
The 1st Press Release of SECRETed project has been published (download it here). The 1st Press Release was motivated by the Kick-off meeting of the SECRETed project and summarizes the objectives of the project and the contribution of all partners to the Work […]
In contexts of IUPAC|CCCE 2021 conference, Eberhard Karls Universität Tübingen co-organized with Queen’s University (Canada), the Symposium of “Natural Products: From Discovery to Application”. The event was focused on the discovery and development of Natural Products as therapeutics and will […]
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Sustainable Exploitation of bio-based Compounds Revealed and Engineered from naTural sources Topic: FNR-11-2020 Prospecting aquatic and terrestrial natural biological resources for biologically active compounds
This Project has received funding from the European Community’s H2020 Programme under the grant agreement No. 101000794. The material presented and views expressed here are the responsibility of the author(s) only. Funding Scheme: H2020-FNR-2020-2.
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